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Title: | Computational analysis of short-chain Dehydrogenase/Reductase Enzyme gene from Plutella Xylostella. |
Authors: | Khairurmisa Atiqah Mohamad Khalid Maizom Hassan Zeti-Azura Mohamed-Hussein |
Conference Name: | 9th International Conference on Plant Protection in the Tropics |
Keywords: | Plutella Xylostella short-chain dehydrogenase juvenile hormone bioinformatic analysis structure prediction |
Conference Date: | 03/08/2016 |
Conference Location: | Hilton Hotel, Kuching, Sarawak, Malaysia |
Abstract: | Plutella Xylostella (L.) (Lepidoptera: Plutellidae) is the most destructive cosmopolitan insect pests for brassicaceous crops. Juvenile hormone (JH) is an acyclic sesquiterpene group hormones secreted by Corpora Allata (CA) that regulates the physiology of an insect. The putative short-chain dehydrogenase/ reductase from Plutella Xylostella (PxSDR) gene sequence was obtained from KONAGAbase by using Aedes aegypti (AaSDR-2) as query sequence. This sequence was analysed using standard bioinformatic tools. Domain and profile analysis have identified several residue that play a role in coenzyme binding (Thrll, Gly12, A1a13, Ser14, Ser15, Gly16, 11e17, Gly18) and adenine coenzyme binding site (Asp67). Arg37 has been identified as being key residue in cP2 superfamily. Meanwhile, several residues were also been identified as being involved in the stabilization of its structure. |
Call Number: | kat sem S 494.5 .S86 .H433 |
Publisher: | Malaysian Plant Protection Society |
Appears in Collections: | Seminar Papers/ Proceedings / Kertas Kerja Seminar/ Prosiding |
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