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https://ptsldigital.ukm.my/jspui/handle/123456789/576812
Title: | Potential of 3’-fluoro-3’ deoxythymidine as a cellular proliferation marker in pet oncology examination |
Authors: | Hishar H (UPM) R. Price Fathinul Fikri A. S (UPM) Eddie Lau W. F Assunta C A. J. Nordin (UPM) |
Keywords: | F-FLT 18 F-FDG Positron Emission Tomography (PET) Cellular proliferation |
Description: | Development of the positron emission tomography (PET) diagnostic radiopharmaceutical (18F)fluoro-2-deoxy-D-glucose (18F-FDG) subsequently facilitated the discovery and clinical evaluation of several new tracers as imaging markers for cancer. While 18F-FDG is a widely employed marker for enhanced intracellular glycolysis and metabolic function, one of the newer tracers, (18F)-3’-fluoro-3’ deoxythymidine (18F-FLT), has been developed as a biomarker for cell proliferation. In this review, the potential of 18F-FLT as a biomarker for cancer imaging is discussed. |
News Source: | Pertanika Journals |
ISSN: | 0128-7680 |
Volume: | 24 |
Pages: | 41-52 |
Publisher: | Universiti Putra Malaysia |
Appears in Collections: | Journal Content Pages/ Kandungan Halaman Jurnal |
Files in This Item:
File | Description | Size | Format | |
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ukmvital_82465+Source01+Source010.PDF | 417.61 kB | Adobe PDF | View/Open |
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