Please use this identifier to cite or link to this item: https://ptsldigital.ukm.my/jspui/handle/123456789/576812
Title: Potential of 3’-fluoro-3’ deoxythymidine as a cellular proliferation marker in pet oncology examination
Authors: Hishar H (UPM)
R. Price
Fathinul Fikri A. S (UPM)
Eddie Lau W. F
Assunta C
A. J. Nordin (UPM)
Keywords: F-FLT
18 F-FDG
Positron Emission Tomography (PET)
Cellular proliferation
Description: Development of the positron emission tomography (PET) diagnostic radiopharmaceutical (18F)fluoro-2-deoxy-D-glucose (18F-FDG) subsequently facilitated the discovery and clinical evaluation of several new tracers as imaging markers for cancer. While 18F-FDG is a widely employed marker for enhanced intracellular glycolysis and metabolic function, one of the newer tracers, (18F)-3’-fluoro-3’ deoxythymidine (18F-FLT), has been developed as a biomarker for cell proliferation. In this review, the potential of 18F-FLT as a biomarker for cancer imaging is discussed.
News Source: Pertanika Journals
ISSN: 0128-7680
Volume: 24
Pages: 41-52
Publisher: Universiti Putra Malaysia
Appears in Collections:Journal Content Pages/ Kandungan Halaman Jurnal

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