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2. PHD Thesis / Tesis PHD
3. Faculty of Health Sciences / Fakulti Sains Kesihatan

Title:	Analysis method for laryngeal high-speed videoendoscopy : development of measurement protocol and application in evaluating vocal fold vibration among different groups of normophonic individuals
Supervisor:	Kartini Ahmad, Professor Dr.
Keywords:	Endoscopes Universiti Kebangsaan Malaysia -- Dissertations Dissertations, Academic -- Malaysia
Issue Date:	30-Aug-2020
Description:	Although poised with clear advantages, laryngeal high-speed videoendoscopy (LHSV) has not yet been accepted as a routine imaging tool for the evaluation of vocal fold vibration. The main hindrance to the widespread clinical adoption is the unavailability of methods to analyze the huge amount of images from the LHSV effectively. Recently, a promising LHSV-based analysis method has been introduced. This analysis method quantifies glottal area waveforms (GAW), extracted from the LHSV images, to generate LHSV-based measures (i.e., F0GAW, jitterGAW, shimmerGAW, OQGAW, and Nyquist plot) that are applicable in describing the vocal fold vibration. The ability of this analysis method in studying the vocal fold vibratory behaviors had been substantially demonstrated. However, the other utility aspects for clinical application still require further attention. Most fundamental is the measurement protocol for this analysis method is still inconclusive, of which the criteria for the analysis input i.e., a segment of interest (SOI), has not been fully defined. Particularly, the length of the SOI and the location within the image sample, where it needs to be selected, still need to be determined. Meanwhile, the analysis using any option of a well-delineated glottal area and images visualizing a partial view of the glottis (i.e., posterior-middle, anteriormiddle, and middle), demand further verification. Also, within the measurement protocol, the incomplete description of the Nyquist plot requires refinement. While inconclusiveness is evident in the measurement protocol, inadequacy is found in the LHSV-based measures of groups of normophonic individuals i.e., normal speakers and singers. In normal speakers, the normative LHSV-based measures are still insufficient for reliable clinical decision. Whereas among singers, the LHSV-based measures and their comparison to those of normal speakers are virtually absent. Therefore, the encompassing aim of this work is to establish the two clinical utility aspects above, which would be presented in three studies. Two studies aimed to address the unresolved issues in the measurement protocol i.e., criteria for the SOI and description of the Nyquist plot. The third study focuses on obtaining the LHSV-based measures among normal speakers and singers, across gender. The participants consisted of 56 normal speakers (20 males and 36 females) and 13 singers (7 males and 6 females). The methods involved LHSV recording of the vibrating vocal folds. The captured images were measured using this analysis method. The LHSV-based measures from the analyses were compared according to the specified procedures of each study. The results indicated that 2000 frames should be used as the SOI length. The frames could be selected at any location within the image sample depicting well-delineated glottal areas. It was found that, apart from the F0GAW, jitterGAW, and shimmerGAW, the other LHSVbased measures from the analyses of images visualizing the partial view of the glottis require careful interpretation. Also, a more comprehensive description of the Nyquist plot was made available. The results also presented the normative LHSV-based measures of normal speakers across gender, and their comparison to those of singers, which showed that singers might have more refined vibratory dynamics. The present study offers a more conclusive measurement protocol for this analysis method and more complete LHSV-based measures among different groups of normophonic individuals. With the evidential supports from the current findings, this analysis method is one step closer to clinical application, which in turn promotes LHSV as a reliable laryngeal imaging tool in a clinical setting.,Ijazah Doktor Falsafah
Pages:	198
Call Number:	9 Tesis WB26.K45a 2020
Publisher:	UKM, Kuala Lumpur
Appears in Collections:	Faculty of Health Sciences / Fakulti Sains Kesihatan

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