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https://ptsldigital.ukm.my/jspui/handle/123456789/519731| Title: | A longitudal analysis of pressurized wideband absorbance measures in healthy young infants |
| Authors: | Hamzah Abdulhameed Wali (P74918) |
| Supervisor: | Rafidah Mazlan, Assoc. Prof. Dr. |
| Keywords: | Wideband absorbance middle ear disorders Dissertations, Academic -- Malaysia |
| Issue Date: | 15-Sep-2017 |
| Description: | Wideband absorbance (WBA) measures are an emerging technology for assessing the outer and middle ear in humans which can be performed under ambient pressure or pressurized conditions. While earlier studies focused on measuring WBA at ambient pressure in young infants aged 0 to 6 months, the application of pressurized WBA in this population has not been systematically investigated. In addition, studies examining the effects of age and ethnicity on pressurized WBA in young infants are scarce. Thus, this thesis aimed to: (1) investigate age and ethnic disparities, (2) compare between WBA measured at tympanometric peak pressure (TPP) and 0 daPa, (3) determine the test-retest reliability of WBA, and (4) establish pressurized normative WBA data in young infants aged 0-6 months using a longitudinal experimental design. In the first phase of the study, 99 neonates from the maternity ward of Hospital Kuala Lumpur were tested using high frequency tympanometry (HFT), acoustic stapedial reflex (ASR), distortion product otoacoustic emissions (DPOAE) and pressurized WBA. Of the 99 neonates, 58 were Malays, 28 were Indians, and 13 were Chinese. In the second phase of the study, 44 infants were re-assessed using HFT, ASR, DPOAE and pressurized WBA at 1, 2, 3, 4, 5 and 6 months of age. When measuring WBA under pressurized conditions, WBA at TPP and 0 daPa from 250 to 8000 Hz were recorded and analyzed. In the first phase of the study, a mixed-model analysis of variance (ANOVA) fitted to the data obtained from the 99 neonates demonstrated no significant main effect of ethnicity on pressurized WBA at both TPP and 0 daPa. In the second phase of the study, a linear mixed model analysis fitted to the data obtained from the 44 infants showed a significant age effect during the first six months of life at TPP and 0 daPa, with WBA between 2000 and 5000 Hz increased with age. Also, a comparison between WBA measured at TPP and 0 daPa for each age group showed a significant difference between the two measurements at frequencies below 2 kHz. Thus, two sets of preliminary normative data were established for WBA at TPP and 0 daPa for three age groups: neonates, infants aged 1-2 months, and infants aged 3-6 months. Analysis of test-retest reliability using Intraclass Correlation Coefficient (ICC) revealed that WBA is a reliable measure with ICC values ranging from 0.64 to 0.99. In conclusion, this study has enhanced the understanding on the use of pressurized WBA in young infants. The normative data developed in the study may be useful in identifying young infants with middle ear disorders.,Doktor Falsafah |
| Pages: | 149 |
| Call Number: | WS430.H232l 2017 9 |
| Publisher: | UKM, Kuala Lumpur |
| Appears in Collections: | Faculty of Health Sciences / Fakulti Sains Kesihatan |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| A Longitunidal Analysis Of Pressurized Wideband Absorbance Measures In Healthy Young Infants.pdf Restricted Access | 1.92 MB | Adobe PDF |  View/Open |
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