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https://ptsldigital.ukm.my/jspui/handle/123456789/457468| Title: | The heritability of palatal rugae morphology amongst siblings : a 3-dimensional approach |
| Authors: | Chong Jun Ai (P91617) |
| Supervisor: | Alizae Marny Fadzlin Syed Mohamed, Dr. |
| Keywords: | Palate Morphology Universiti Kebangsaan Malaysia -- Dissertations Dissertations, Academic -- Malaysia |
| Issue Date: | 2-Sep-2020 |
| Description: | Although there is clinical applicability of the palatal rugae as a stable reference area in evaluating orthodontic tooth movement, controversy still exist whether the palatal rugae is stable or variable. Heritability estimate (h2) expresses the proportion of phenotypic variance that is due to nature or nurture. Thus, research should be directed towards environmental factors if rugae patterns show trivial heritability. The aim of this study is to compare the palatal rugae morphology between full-siblings and the proportion of variability of the rugae morphology that is due to genetic variation. This cross-sectional study was conducted on digital models of 162 siblings aged 15-30 years old. The position, length, shape, direction and unification of the palatal rugae were assessed with Thomas and Kotze, 1983 classification using Geomagic Studio software (3D Systems, Rock Hill, SC, USA). The palatal rugae morphology between siblings showed significantly similar characteristics for total number of left rugae, left primary rugae, bilateral secondary rugae, right straight rugae and right convergent rugae accounting for at least 6.25%-12.8% of the variability due to heredity. Despite the similarities found, the palatal rugae patterns showed significant differences between siblings of at least 46.9% (p=0.001). Zero heritability was found in 9 of the 14 rugae patterns. Meanwhile, total number of rugae, primary, backward and convergent rugae showed moderate heritability (h2>0.3) and total number of secondary rugae showed high heritability (h2>0.6). In conclusion, the palatal rugae patterns were both environmentally and genetically influenced,Ijazah Sarjana Doktor Pergigian Klinikal (Ortodontik) |
| Pages: | 82 |
| Call Number: | WV410.C545h 2020 9 tesis |
| Publisher: | UKM, Kuala Lumpur |
| Appears in Collections: | Faculty of Dentistry / Fakulti Pergigian |
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|---|---|---|---|---|
| ukmvital_127471+Source01+Source010.PDF Restricted Access | 1.34 MB | Adobe PDF |  View/Open |
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