Please use this identifier to cite or link to this item:
https://ptsldigital.ukm.my/jspui/handle/123456789/579006| Title: | Xanthones from calophyllum inophyllum |
| Authors: | Kar Wei Lee (UPM) Gwendoline Cheng Lian Ee (UPM) Shaari Daud (UTM & UITM) Thiruventhan Karunakaran (UPM) |
| Keywords: | Anti-inflammatory Antimicrobial Calophyllum inophyllum Xanthones |
| Issue Date: | Feb-2017 |
| Description: | Repeated separation and purification of fractions from the crude chloroform extract of Calophyllum inophyllum via column chromatography afforded five known xanthone caloxanthones A, B, C, macluraxanthone and pyranojacareubin. Structural elucidations and determination of the isolated compounds were supported by spectral analyses obtained by subjecting the compounds to various spectroscopic techniques. The chloroform extract, when tested against RAW264.7 cells for anti-inflammatory potentials, exhibited the most promising activity with an IC50 value of 14.81±0.04 ?g/mL compared to moderate activities shown by the ethyl acetate and n-hexane extracts. Antimicrobial tests showed that the n-hexane and chloroform extracts acted moderately against Staphylococcus epidermidis S273 and Bacillus subtilis B145. |
| News Source: | Pertanika Journal of Social Sciences & Humanities |
| ISSN: | 1511-3701 |
| Volume: | 40 |
| Pages: | 111-118 |
| Publisher: | Universiti Putra Malaysia Press |
| Appears in Collections: | Journal Content Pages/ Kandungan Halaman Jurnal |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| ukmvital_85806+Source01+Source010.PDF | 378.69 kB | Adobe PDF |  View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.