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Please use this identifier to cite or link to this item: https://ptsldigital.ukm.my/jspui/handle/123456789/579006
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dc.contributor.authorKar Wei Lee (UPM)
dc.contributor.authorGwendoline Cheng Lian Ee (UPM)
dc.contributor.authorShaari Daud (UTM & UITM)
dc.contributor.authorThiruventhan Karunakaran (UPM)
dc.date.accessioned2023-11-06T03:12:26Z-
dc.date.available2023-11-06T03:12:26Z-
dc.date.issued2017-02
dc.identifier.issn1511-3701
dc.identifier.otherukmvital:85806
dc.identifier.urihttps://ptsldigital.ukm.my/jspui/handle/123456789/579006-
dc.descriptionRepeated separation and purification of fractions from the crude chloroform extract of Calophyllum inophyllum via column chromatography afforded five known xanthone caloxanthones A, B, C, macluraxanthone and pyranojacareubin. Structural elucidations and determination of the isolated compounds were supported by spectral analyses obtained by subjecting the compounds to various spectroscopic techniques. The chloroform extract, when tested against RAW264.7 cells for anti-inflammatory potentials, exhibited the most promising activity with an IC50 value of 14.81±0.04 ?g/mL compared to moderate activities shown by the ethyl acetate and n-hexane extracts. Antimicrobial tests showed that the n-hexane and chloroform extracts acted moderately against Staphylococcus epidermidis S273 and Bacillus subtilis B145.
dc.language.isoen
dc.publisherUniversiti Putra Malaysia Press
dc.relation.haspartPertanika Journal of Social Sciences & Humanities
dc.relation.urihttp://www.pertanika.upm.edu.my/regular_issues.php?jtype=1&journal=JTAS-40-1-2
dc.rightsUniversiti Putra Malaysia
dc.subjectAnti-inflammatory
dc.subjectAntimicrobial
dc.subjectCalophyllum inophyllum
dc.subjectXanthones
dc.titleXanthones from calophyllum inophyllum
dc.typeJournal Article
dc.format.volume40
dc.format.pages111-118
dc.format.issue1
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