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https://ptsldigital.ukm.my/jspui/handle/123456789/578994| Title: | Silicon nanowire interface circuit for dna detection |
| Authors: | Kamilu Iman Usman (UPM) Mohd Nizar Hamidon (UPM) Siti Fatimah Abd Rahman (UPM UNIMAP) Guan Ling Sim (UPM) |
| Keywords: | Silicon nanowire Nanoelectronics Interface circuit DNA detection |
| Issue Date: | Feb-2017 |
| Description: | Detection and quantification of DNA is critical to many areas of life sciences and health care, from disease diagnosis to drug screening. The transduction of DNA through electrochemical methods have a fast response rate and with a conductometric device like the silicon nanowire which can be fabricated to have a similar diameter of the DNA molecule being targeted, detection is real-time. Critical to this is the interfacing of a current-source and an amplifier capable of achieving a maximum of 10 pico ampere input bias. In this project, we fabricated a silicon nanowire using the top down approach and built a circuit that can mimic the output signal as low as 12 nA and achieved a gain of 1 million to be interfaced with the nanowire for real-time DNA detection. |
| News Source: | Pertanika Journals |
| ISSN: | 0128-7680 |
| Volume: | 25 |
| Pages: | 251-258 |
| Publisher: | Universiti Putra Malaysia Press |
| Appears in Collections: | Journal Content Pages/ Kandungan Halaman Jurnal |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| ukmvital_116380+Source01+Source010.PDF | 501.16 kB | Adobe PDF |  View/Open |
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