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https://ptsldigital.ukm.my/jspui/handle/123456789/500491Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.advisor | Wan Yaacob Wan Ahmad, Associate Prof. | - |
| dc.contributor.author | Mohammed Yahya Abdo (P64539) | - |
| dc.date.accessioned | 2023-10-13T09:44:22Z | - |
| dc.date.available | 2023-10-13T09:44:22Z | - |
| dc.date.issued | 2017-02-15 | - |
| dc.identifier.other | ukmvital:120903 | - |
| dc.identifier.uri | https://ptsldigital.ukm.my/jspui/handle/123456789/500491 | - |
| dc.description | A phytochemical survey to detect alkaloids was performed on 301 plant parts of 113 species. From these, 11 species (9.7%) were found to be positive in alkaloids, of which 4 have not been screened before. The alkaloid extract of Actinodaphne sesquipedalis stem bark produced glaunine. Chemical study of Hedychium malayanum stem and leaf extracts gave stigmasterol, sitostenone, stigmast-4-ene-3,6-dione, lupenone and caryophyllene oxide. The compound structures were elucidated by spectroscopic means, and by comparison with the literature data. Essential oils of fresh parts of Hedychium malayanum, Elettariopsis triloba, E. smithiae, Amomum sp., Zingiber sp. and Z. besar var. besar and from the leaves of Z. besar var. fraseri, Z. besar var. nervifolium and Z. belumensis were hydrodistilled and analysed by capillary GC and GC-MS using DB-5 column. Monoterpenoids dominated H. malayanum oils with 1,8- cineole was the main compound in rhizomes (37.7%), and β-pinene in the stem (46.7%) and leaves (39.1%). The respective rhizome and stem oils of E. triloba were predominated by sesquiterpenoids and marked by o-cymene (12.5%) and α-cissantalol (9.5%). The E. triloba leaf oil was found to consist mainly of monoterpenoids, with β-phellandrene representing more than half (56.2%). The profiles of E. smithiae oils were dominated by monoterpenoids with the major contributors being α-pinene (46.0%) in the rhizomes and linalool (12.8%) in the leaves. The rhizome and leaf oils of Amomum sp. were principally monoterpenoids, with β-pinene (41.2 and 28.8%, respectively) being the most prominent constituent in both. Its stem oil contained high levels of sesquiterpenoids, but mainly consisted of monoterpenic β-pinene (16.3%). The oils from Zingiber sp. were characterized by the occurrence of linalool in the rhizomes (10.6%), limonene in the stem (14.8%) and flowers (28.8%) and β-pinene in the leaves (35.1%). Regarding the Z. besar var. besar oils, β-caryophyllene (19.7%) was the most abundant in the rhizomes, β-bisabolene (17.6%) in the stem and β-pinene (41.9%) in the flowers. The leaf oils of Z. besar var. besar (6 samples of different smells), Z. besar var. fraseri, Z. besar var. nervifolium and Z. belumensis gave significantly different GC chromatograms, but with the same major compound of βpinene (56.9%; average). The antioxidant and antibacterial activities of 7 alkaloid extracts, consecutive extracts from different parts of H. malayanum, and essential oils were evaluated. Among the alkaloid extracts, A. sesquipedalis stem bark showed the highest radical scavenging activity (RSA), ferrous ion chelating (FIC) and ferric reducing antioxidant power (FRAP). For H. malayanum extracts, the strongest activities of RSA, FRAP and total phenolic content (TPC) were observed by leaf methanol followed by leaf n-hexane and stem n-hexane. In FIC test, the reverse was true. Out of the oils examined, H. malayanum rhizomes displayed the greatest RSA, FIC and β-carotene bleaching (BCB). Disc-diffusion and micro-dilution tests using 6 bacteria strains showed that the alkaloid extract of A. sesquipedalis stem bark exhibited the strongest antibacterial activity, with Staphylococcus aureus being the most sensitive. The above three H. malayanum extracts that gave the highest RSA, FRAP and TPC values also exerted the strongest bacteriostatic against 7 bacteria. They strongly inhibited the growth of Bacillus subtilis. The highest antibacterial activity of the oils was shown by E. smithiae leaves against S. aureus and Serratia marcescens among 8 microorganisms.,Certification of Masters/ Doctorial Thesis" is not available | - |
| dc.language.iso | eng | - |
| dc.publisher | UKM, Bangi | - |
| dc.relation | Faculty of Science and Technology / Fakulti Sains dan Teknologi | - |
| dc.rights | UKM | - |
| dc.subject | Universiti Kebangsaan Malaysia -- Dissertation | - |
| dc.subject | Dissertations, Academic -- Malaysia | - |
| dc.subject | Botanical chemistry | - |
| dc.subject | Zingiberaceae | - |
| dc.subject | Alkaloids-Synthesis | - |
| dc.title | Phytochemical study of several alkaloid-containing plants and zingiberaceae | - |
| dc.type | Theses | - |
| dc.format.pages | 266 | - |
| dc.identifier.callno | QK898.A4A236 2017 tesis | - |
| dc.identifier.barcode | 003056 (2017) | - |
| Appears in Collections: | Faculty of Science and Technology / Fakulti Sains dan Teknologi | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| ukmvital_120903+SOURCE1+SOURCE1.0.PDF Restricted Access | 2.04 MB | Adobe PDF |  View/Open |
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