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https://ptsldigital.ukm.my/jspui/handle/123456789/457472| Title: | The Relationship of Salivary Urea Levels and Dental Calculus Index in Children with Chronic Kidney Disease Stage Five |
| Authors: | Katherine Kong Loh Seu (P66136) |
| Supervisor: | Alida Mahyuddin, Dr. |
| Keywords: | Oral hygiene status Chronic Kidney Disease Dissertations, Academic -- Malaysia |
| Issue Date: | 15-May-2015 |
| Description: | The objectives of this cross sectional, case-control study were to determine the oral hygiene status, the extent of calculus deposition, salivary urea levels as well as the associations between salivary and serum urea, dental calculus, oral hygiene habits and type and duration of Chronic Kidney Disease (CKD) stage five treatment in CKD stage five child patients. CKD stage five child patients from HKL and matched healthy children from UKM Dental Polyclinic were recruited. Patients were examined clinically and the criteria utilised were Simplified Debris Index (DI-S), Simplified Calculus Index (CI-S), Simplified Oral Hygiene Index (OHI-S) and Volpe-Manhold Index (VMI). Subjects were asked to record daily oral hygiene habits and unstimulated saliva samples were collected for the analysis of urea concentration. Related clinical and laboratory information were also extracted from patients’ medical records. The salivary urea was quantitatively measured using the technique consisted of Jung reagent and spectrophotometry. A total of 33 (33.3%) CKD stage five child patients and 66 (66.7%) healthy subjects participated in the study. The oral hygiene status was found to be similar between the two groups but CKD stage five child patients had significantly higher calculus deposition (CI-S: 0.35 ± 0.29) as compared to healthy controls (CI-S: 0.27 ± 0.34), p < 0.05. Salivary urea of CKD stage five child patients was 10 to 20 folds higher than in controls (15.13 ± 5.67 mmol/L and 1.34 ± 0.91 mmol/L respectively, p < 0.01). In addition, a statistically significant association was found between salivary and serum urea of CKD stage five patient (rs = 0.513, p < 0.01). However, no statistically significant association was found between calculus deposition and salivary urea levels, oral hygiene habits, type and duration of CKD stage five treatment in these patients. High salivary urea levels had been documented as being one of the contributing factors for calculus formation. However, in this study, the calculus deposits in CKD stage five child patients are not significantly associated with the high salivary urea levels. One of the causal factors for the low to moderate levels of calculus deposits found in CKD stage five children is most probably due to poor oral health awareness in their parents. Improvement in the multidisciplinary management of CKD stage five child patients involving both medical and dental personnel are thus required to ensure optimum oral health in these patients.,Ijazah Doktor Pergigian Klinikal (Pergigian Pediatrik) |
| Pages: | 83 |
| Call Number: | WU113.K19r 2015 9 |
| Publisher: | UKM, Kuala Lumpur |
| Appears in Collections: | Faculty of Dentistry / Fakulti Pergigian |
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|---|---|---|---|---|
| ukmvital_83935+Source01+Source010.PDF Restricted Access | 169.46 kB | Adobe PDF |  View/Open |
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